Mucosal tears and colonic perforation in a patient with collagenous colitis

Mucosal tears and colonic perforation in a patient with collagenous colitis.

Collagenous colitis, which is clinically characterized by chronic non-bloody diarrhea, is a variant of microscopic colitis. It can be diagnosed on histological grounds, with thickening of the subepithelial collagen layer [1–3]. The colonic mucosa is usually endoscopically normal, although minor abnormalities such as edema or erythema can be seen [2,3]. Serious complications are rare. A 69-year-...

Spontaneous colonic perforation in a patient with collagenous colitis.

An otherwise healthy woman, age 67 years, presented in 2009 with the complaint of loose, nonbloody stools of 2 months’ duration. The patient reported having up to 6 bowel movements daily that sometimes occurred at night and were accompanied by lower abdominal cramping and urgency. The symptoms were not associated with food intake. The patient took aspirin but no other nonsteroidal anti-inflamma...

Mucosal tears during colonoscopy in a patient with ulcerative colitis.

of bloody diarrhea. Except for partial gastroduodenectomy because of a duodenal ulcer, the subject was healthy and was not taking any regular medication. He had not recently visited any foreign countries. Physical examination was unremarkable. Routine laboratory tests and complete blood analysis were normal. Total colonoscopy was performed after standard bowel preparation, without sedation. Col...

Collagenous colitis with mucosal tears on endoscopic insufflation: a unique presentation.

Collagenous colitis with mucosal ulcerations in a patient without nonsteroidal anti-inflammatory drug or lansoprazole use

Chronic watery diarrhea combined with normal-appearing colonic mucosa at endoscopy with abnormal histopathology is classified as microscopic colitis. Microscopic colitis encompasses both collagenous and lymphocytic colitis. A 42-year-old Caucasian woman presented with severe diarrhea for six weeks with loose watery stools every 1-2 h, approximately 15 episodes per day. She denied any melena or ...